Leitung: Prof. Dr. Beate Röder

Humboldt-Universität zu Berlin
Institut für Physik
AG Photobiophysik
Newtonstraße 15
12489 Berlin


Tel.: 030 - 2093 82079
Fax: 030 - 2093 7666

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  • Ben-Dror S, Bronshtein I, Wiehe A, Röder B, Senge MO, Ehrenberg B

    On the correlation between hydrophobicity, liposome binding and cellular uptake of porphyrin sensitizers

    Photochem. Photobiol 82 (3): 695-701 2006

  • B. Röder

    Photosensibilisatoren für die Photodynamische Therapie

    Kapitel in: Angewandte Lasermedizin, Lehr- und Handbuch für Praxis und Klinik, eds.: LMZ -- H.-P. Berlien, H. Müller, ecomed Verlag, München-Landsberg, 20. Erg. Lfg. 03/06, III - 3.15.1, S. 1-12

  • E.A. Ermilov, S. Tannert, Th. Werncke, M.T.M. Choi, D.K.P. Ng, B. Röder

    Photoinduced Electron and Energy Transfer in a New Porphyrin-Phthalocyanine Triad

    Chemical Physics 328 (2006) 428-437

  • B. Röder, E. Ermilov, M. Regehly, M. Helmreich, N. Jux, F. Rancan, F. Böhm

    Pheophorbide a - fullerene C60 hexadduct molecular systems as part of modular carrier systems for PDT

    J. Porphyrins Phthalocyanines 2006; 10: 499

  • N. Jux, M. Helmreich, A. Hirsch, B. Röder, E. Ermilov

    Novel oligo-pyropheophorbide fullerene conjugates

    J. Porphyrins Phthalocyanines 2006; 10: 465

  • D. Wöhrle, S. Makarov, B. Röder, Ch. Litwinski, E. Ermilov, O. Suvorova

    Novel NIR-absorbing annulated multinuclear phthalocyanines

    J. Porphyrins Phthalocyanines 2006; 10: 421

  • I.A. Kaputskaya, E.A. Ermilov, S. Tannert, B. Röder, S.K. Gorbatsevich

    Spectral, kinetic and polarization characteristics of luminescence of acriflavine in polymeric matrix under pulsed excitation with different durations and intensities.

    Chem. Phys., 327, 2006, 171-179.

  • B. Röder, E.A. Ermilov, St. Hackbarth, M. Helmreich, N. Jux

    Trap formation and energy transfer in pheophorbide a-DAB-dendrimers and pyropheophorbide a-fullerene C60 hexaadduct molecular systems.

    SPIE, 6192 (2006) 495-507

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  • S. Lombardi Borgia, M. Regehly, R. Sivaramakrishnan, W. Mehnert, H.C. Korting, K. Danker, B. Röder, K.D. Kramer, M. Schäfer-Korting

    Lipid nanoparticles for skin penetration enhancement-correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy

    Journal of Controlled Release 110 (2005) 151-163

  • A. Zeug, M. Meyer, P.C. Lo, D.K.P. Ng, B. Röder

    Fluorescence anisotropy and transient absorption of halogenated silicon(IV) phthalocyanines with axial poly(ethyleneglycol) substituents

    J. Porphyrins Phthalocyanines 9 (2005) 298-302

  • F. Rancan, M. Helmreich, A. Mölich, N. Jux, A. Hirsch, B. Röder, C. Witt, F. Böhm

    Fullerene-pyropheophorbide a complexes as sensitizer for photodynamic therapy: Uptake and photo-induced cytotoxicity on Jurkat cells.

    Journal of Photochemistry and Photobiology B: Biology,
    Volume 80, Issue 1 , 01 July 2005, Pages 1-8

  • M. Helmreich, E.A. Ermilov, M.Meyer, N. Jux, A. Hirsch, B. Röder

    Dissipation of electronic excitation energy within a C60 [6:0]-hexaadduct carrying twelve pyropheophorbide a moieties.

    J. Am. Chem. Soc. 127 (2005) 8376-8385

  • E.A. Ermilov, St. Hackbarth, S. Al-Omari, M. Helmreich, N. Jux, A. Hirsch, B. Röder

    Trap formation and energy transfer in the hexapyropheophorbide a - fullerene C60 hexaadduct molecular system.

    Optics Communications 250 (2005) 95-104

  • S. Hackbarth, E.A. Ermilov, B. Röder

    Interaction of Pheophorbide a molecules covalently linked to DAB dendrimers

    Optics Communications 248 (2005) 295-306

  • Fiorenza Rancan, Arno Wiehe, Maria Nöbel, Mathias O. Senge, Saleh Al Omari, Fritz Böhm, Matthias John, Beate Röder

    Influence of substitutions on asymmetric dihydroxychlorins with regard to intracellular uptake, subcellular localization and photosensitization of Jurkat cells

    Journal of Photochemistry and Photobiology B: Biology,
    Volume 78, Issue 1 , 14 January 2005, Pages 17-28

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2002 ... 2004

  • S. Tannert, S. Hackbarth, E. Ermilov, B. Röder

    Energy migration on pheophorbide a loaded DAB Demdrimers

    J. Porphyrins Phthalocyanines 2004; 8: 860

  • M. Helmreich, E. Ermilov, F. Rancan, F. Böhm, B. Röder, A. Hirsch, N. Jux

    Systhesis and photophysics of fullerene-dendrimer-pyropheophorbide-conjugates

    J. Porphyrins Phthalocyanines 2004; 8: 689

  • B. Röder, S. Hackbarth, A. Wiehe, F. Rancan, N. Jux, M. Helmreich, A. Hirsch, E. Ermilov, M.O. Senge, M. Nöbel, S. al Omari, K, Simonenko

    Influence of tetrapyrrole amphiphicility on membrane localization and the mechanism of photosensitized cell death

    J. Porphyrins Phthalocyanines 2004; 8: 472

  • S. Al Omari, E.A. Ermilov, M. Helmreich, N. Jux, A. Hirsch and B. Röder

    Transient absorption spectroscopy of a monofullerene C60-bis-(pyropheophorbide a) molecular system in polar and nonpolar environments

    Applied Physics B: Lasers and Optics, Volume 79 (2004), Number 5, Page 617-622

  • Andrea Paul, Steffen Hackbarth, Rolf D. Vogt, Beate Röder, B. Kent Burnison and Christian E. W. Steinberg

    Photogeneration of singlet oxygen by humic substances: comparison of humic substances of aquatic and terrestrial origin

    Photochem. Photobiol. Sci., 2004, 3, 273

  • E.A. Ermilov, S. Al-Omari, M. Helmreich, N. Jux, A. Hirsch, B. Röder

    Photophysical properties of fullerene - dendron - pyropheophorbide supramolecules

    Chem. Phys. 301 (2004) 27-31

  • E.A. Ermilov, S. Al-Omari, M. Helmreich, N. Jux, A. Hirsch, B. Röder

    Steady-state and time-resolved studies on the photophysical properties of fullerene-pyropheophorbide a complexes in polar and nonpolar solvents

    Opt. Commun. 234 (2004) 245-252

  • G. Li , S. V. Bhosale, T. Wang, S. Hackbarth, B. Roeder, U. Siggel and J.-H. Fuhrhop

    Form-Stable Nanometer Gaps on Silica Nanoparticles Containing, Porphyrin-Quinone and Porphyrin-Metalloporphyrin Heterodimer Distances of Zero, Five and Ten Ångstroms

    J.Am.Chem. Soc. 125 (2003)10693-10702

  • Zimmermann J., Siggel U., Fuhrhop J. H. and Röder B.

    Excitonic Coupling between B and Q Transitions in a Porphyrin Aggregate.

    J. Phys. Chem. B 107 (2003) 6019-6021

  • Zimmermann J., Zeug A. and Röder B.

    A generalization of the Jablonski diagram to account for polarization and anisotropy effects in time-resolved experiments.

    Phys. Chem. Chem. Phys. 5 (2003) 2964-2969

  • Chen Y., Hanack M., O'Flaherty S., Bernd G., Zeug A., Röder B., Blau W.J.

    An Axially Grafted Charm Bracelet Type Indium Phthalocyanine Copolymer.

    Macromolecules, 36 (2003) 3786-3788.

  • Fuchs H., Zimmermann J., Röder B.

    Experimental determination of the orientation of excited state transition dipoles in tetrapyrroles with different molecular symmetries.

    Optics Communications, 220 (2003) 119-127

  • Lo P., Wang S., Zeug A., Meyer M., Röder B., Ng D. K. P.

    Preparation and Photophysical Properties of Halogenated Silicon(IV) Phthalocyanines Substituted Axially with Poly(ethylene glycol) Chains.

    Tetrahedron Lett., 44 (2003) 1967-1970.

  • Paul A.,Hackbarth S., Mölich A., Luban C., Oelckers S., Böhm F., Röder B.

    Comparative Study on the Photosensitization of Jurkat Cells in vitro by Pheophorbide-a and a Pheophorbide-a Diaminobutane poly-propylene-imine Dendrimer Complex.

    Laser phys., 13 (2003) 22-29.

  • Paul A., Mölich A., Oelckers S., Seifert M., Röder B.

    Alkyl-substituted magnesium-phthalocyanine: III, Phototoxicity after excitation of higher electronic states in cells in vitro.

    J. Porphyrins Phthalocyanines, 6 (2002) 340-346.

  • Zeug A., Zimmermann J., Röder B., Lagorio MG., San Román E.

    Microcrystalline cellulose as a carrier for hydrophobic photosensitizers in water.

    Photochemical & Photobiological Sciences, 1 (2002) 198-203.

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1999 ... 2001

  • Wiehe A., Stollberg H., Runge S., Paul A., Senge M. O., Röder B.

    PDT-Related Photophysical Properties of Conformationally Distorted Palladium(II) Porphyrins.

    J. Porphyrins Phthalocyanines, 5 (2001) 853-860.

  • Wiehe A., Senge M. O., Schäfer A., Speck M., Tannert S., Kurreck H., Röder B.

    Electron Donor-Acceptor Compounds. Exploiting the Triptycene Geometry for the Synthesis of Porphyrin-Quinone Diads, Triads, and a Tetrad.

    Tetrahedron, 57 (2001) 10089-10110.

  • Röder B.

    Grundlagen der Photodynamischen Therapie

    Humboldt Spektrum, 8 (2001) 72-77.

  • Wiehe A., Simonenko E. J., Senge M.O., Röder B.

    Hydrophilicity vs. hydrophobicity - varying the amphiphilic structure of porphyrins related to the photosensitizer m-THPC.

    J. Porphyrins Phthalocyanines, 5 (2001) 758-761.

  • Skupin M., Li G., Fudickar W., Zimmermann J., Röder B., Fuhrhop J.-H.

    Methylammonium Groups at the Solid Walls of Nanometer -Sized, Water-Filled Monolayer Gaps as Binding Sites for a Tetraanionic Porphyrin.

    J. Am. Chem. Soc., 123 (2001) 4354-3461.

  • Zeug A., Paul A., Röder B.

    Observation of the Phase transition in phospholipid liposomes taking advantage of the particular optical properties of octa-a-butyloxy-H2-Phthalocyanines.

    J. Porphyrins Phthalocyanines , 5 (2001) 663-667.

  • Hackbarth, St., Horneffer, V., Wiehe, A., Hillenkamp, F., Röder, B.

    Photophysical properties of Pheophorbide-a-substituted diaminobutane poly-propylene-imine dendrimer.

    Chem. Phys., 269 (2001) 339-346.

  • Zeug A., Rückmann I., Röder B.

    Picosecond transient dichroism and birefringence spectroscopy on pheophorbide-a molecules in solution.

    Opt. B: Quantum Semiclass. Opt., 3 (2001) 251-258.

  • Lagorio M. G., San Román E., Zeug A., Zimmermann J. , Röder B.

    Photophysics on Surfaces: Absorption and Luminescence Properties of Pheophorbide-a on cellulose.

    Phys. Chem. Chem. Phys., 3 (2001) 1524-1529.

  • Korth O., Hanke Th., v. Gersdorff J., Kurreck H., Röder B.

    Photoinduced electron transfer in Langmuir-Blodgett films between the donor 5,10,15,20-Tetra(pentyl-oxy-biphenyl-oxy-m-phenyl)- porphyrinato]zinc(II) and quinone acceptors either separated or linked by acyclohexylene-bridge.

    Thin Solid Films, 382 (2001) 240-245.

  • Röder B.

    Photodynamic therapy, in: Encyclopedia Analytical Chemistry.

    R. A. Meyers (Ed.), pp. 302-320, John Wiley & sons Ltd.,
    Chichester 2000 (inveted contribution)

  • Hackbarth St., Röder B.

    Anisotropy shape control via light quenching and ground state depletion.

    Opt. Commun., 173 (2000) 247-254.

  • Oelckers St., Hanke Th., Röder B.

    Quenching of singlet oxygen in dimethylformamide.

    J. Photochem. Photobiol. A: Chemistry 132 (2000) 29-32.

  • Rohs R., Sklenar H., Lavery R., Röder B.

    Methylene blue binding to DNA with GC alternating base sequence: a modeling study.

    J. Am. Chem. Soc. 122 (2000) 2860-2866.

  • Röder B., Hanke Th., Oelckers St., Hackbarth St., Symietz Ch.

    Photophysical properties of pheophorbide a in solution and in model membrane systems.

    J. Porphyrins Phthalocyanines 4 (2000) 37-44.

  • Eichwurzel I., Stiel H., Röder B.

    Photophysical studies of pheophorbide a dimers.

    J. Photochem. Photobiol. B: Biology 54 (2000) 124-200.

  • Röder, B.

    Einführung in die molekulare Photobiophysik

    Teubner Studienbücher, Teubner Stuttgart, III/1999

  • Camps X., Dietel E., Hirsch A., Pyo S., Echegoyen L., Hackbarth St., Röder B.

    Globular dendrimers involving a C60 core and a tetraphenyl porphyrin function

    Chem. Eur. J. 5 (1999) 2362

  • Korth O., Wiehe A., Kurreck H., Röder B.

    Photoinduced intramolecular electron transfer in covalently linked porphyrin-triptycene-(bis)-quinone diads and triads

    Chem. Phys. 246 (1999) 363-372

  • Rückmann I., Zeug A., v. Feilitzsch T., Röder B.

    Orientational relaxation of pheophorbide-a molecules in the ground and in the first excited state measured by transient dichroism spectroscopy

    Opt. Comm. 170 (1999) 361-372.

  • Oelckers St., Ziegler Th., Michler I., Röder B.

    Time-resolved detection of singlet oxygen luminescence in red cell ghost suspensions: concerning a signal component that can be attributed to 1O2 - luminescence from inside of a native membran

    J. Photochem. Photobiol. B: Biology 53 (1999) 121-127.

  • Fudickar W., Zimmermann J., Ruhlmann L., Röder B., Siggel U., Fuhrhop J.-H.

    Fluorescence quenching and size-selective heterodimerization of a porphyrin adsorbed to gold and embedded in rigid membrane gaps

    JACS 121 (1999) 9539-9545.

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1996 ... 1998

  • Korth O., Hanke Th., Röder B.

    Photophysical investigations of pheophorbide-a embedded in Langmuir-Blodgett mono- and multilayers

    Thin solid films 320 (1998) 305-315.

  • Röder B.

    chapter 1: Biophysical parameters 
    and chapter 2: Phorbides - Individual Data,

    Quantitative Data  of 2nd and 3rd generation photosensitizers for PDT,
    ed.: J.G.Moser, 9 -20 and 35 - 42, Gordon and Breach Science Publ. LTD, 1998

  • Spiller W., Kliesch H., Wöhrle D., Hackbarth St., Röder B.

    Singlet oxygen quantum yields of different photosensitizers in polar solvents and micellar solutions

    J. Porphyrins Phthalocyanines 2 (1998) 145-158.

  • Oelckers St., Gurzadyan G. G., Röder B.

    The use of infrared up-conversion for the detection of 1.3 µm luminescence

    Infrared Phys. & Techn., 39 (1998) 425-431.

  • Stiel H., Volkmer A., Rückmann I., Zeug A., Ehrenberg B., Röder B.

    Non-linear and transient absorption spectroscopy of magnesium(II)-tetrabezoporphyrin in solution

    Opt. Comm. 155 (1998) 135-143

  • Fuhrhop J.-H., Ruhlmann L., Messerschmidt Ch., Fudickar F., Zimmermann J., Röder B.

    Rigidity in synkinetic molecular monolayersof functional lipids containing Angström gaps

    Pure & Appl.Chem. 70 (1998) 2385-2391

  • Rückmann I., Petrauskas M., Korth O., Hanke Th., Röder B.

    Picosecond transient absorption spectroscopy on 132-hydroxy-bacteriopheophor- bide-a-methylester (OH-BPME) molecules in solution and embedded in mixed Langmuir-Blodgett-films

    Opt. Commun. 134 (1997) 379-386

  • Rückmann I., Zeug A., Herter R., Röder B.

    On the Influence of Higher Excited States on the ISC Quantum Yield of Octa-a-alkyloxy–substituted Zn-Phthalocyanine Molecules Studied by Nonlinear Absorption

    Inv. paper:  Photochem. Photobiol. 66 (1997) 576 - 584.

  • Zimmermann J., von Gersdorff J., Kurreck H., Röder B.

    Determination of electron transfer parameters of a covalently linked porphyrin quinone with mesogenic substituents - optical spectroscopic studies in solution

    J. Phoochem. Photobiol. B: Biology 40 (1997), 209-217

  • Oelckers St., Sczepan M., Hanke Th., Röder B.

    Time-resolved detection of singlet oxygen luminescence in red ghost cell suspensions

    J. Photochem. Photobiol. B: Biology 39 (1997) 219-223.

  • Hanke Th., Korth O., Rückmann I., Röder B.

    Properties of mixed 132-hydroxy bacteriopheophorbide a methylester / behenic acid mixed monolayers

    Thin solid films, 299 (1997) 152-160.

  • Rübner A., Kirsch D., Andrees S., Decker W., Röder B.,Spengler B., Kaufmann R., Moser J. G.

    Dimeric cyclodextrin carriers with high binding affinity to porphyrinoid photosensitizers

    J.Incl. Phen. 27 (1997) 69-84.

  • Röder B., Hackbarth St., Korth O., Zimmermann C., Herter R., Hanke Th., Höhne W.

    Photophysical properties of pheophorbide a in different carrier-systems

    SPIE vol. 2625 (1996) 179-186.

  • Decker W., Röder B.

    Theoretical description of interactions between some substituted tetrapyrroles and cyclodextrin dimers

    SPIE vol. 2625 (1996) 402-404.

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1986 ... 1995

  • Korth O., Hanke Th., Rückmann I., Röder B.

    High sensitive and spatially resolved absorption / fluorescence measurements on ultrathin Langmuir-Blodgett-films

    Exp. Techn. Phys.   41 (1995) 25-36.

  • Oelckers St., Hanke Th., Moser J., Röder B.

    Time-resolved detection of singlet oxygen luminescence in red cell ghosts generated by photosensitizers via excitation in the far red

    SPIE vol 2325 (1994) 116-120.

  • Röder B.

    Photosensibilisatoren für die Photodynamische Therapie

    Kapitel in: Angewandte Lasermedizin, Lehr- und Handbuch für Praxis und Klinik,
    eds.: LMZ - Berlien, H.-P., Mhller,H., ecomed Verlag, München-Landsberg,
    6. Erg. Lfg. 2/93, III - 3.15.1, S.1-12

  • Stiel H., Marlow I., Röder B.

    Photophysical properties of the photosensitizer pheophorbide a studied at high photon flux densities

    J. Photochem. Photobiol., B: Biology 17 (1993) 181-186.

  • Dressler C., Möller U., Lewald T., Berlien H.-P. ,Röder B., Risse H.-J.

    Introduction of a simple model for testingimmuno conjugates with photosensitizers

    Lasers in Med. Science 7 (1992) 174.

  • Näther D.U., Gilchrist J.R., Röder B.

    Temporal and spectral separation of singlet oxygen luminescence from near infrared emitting photosensitizers

    J. Photochem. Photobiol. 57 (1992) 1056-1059.

  • Röder B.

    Grundlagen und Probleme der Photodynamischen Therapie

    MEDTECH 2 (1991) 15-19. (invited paper)

  • Röder B., Näther D., Lewald T., Braune M., Freyer W., Nowak Ch.

    Photophysical properties and photodynamic activity in vivo of some tetrapyrroles

    Biophys. Chem., 35 (1990) 303-312.

  • Krasnovsky A. A. (jr.), Neverov K. V., Egorov S. Yu., Röder B., Lewald T.

    Photophysical studies of pheophorbide a and pheophytin a - phosphorescence and photosensitized singlet oxygen luminescence

    J. Photochem. Photobiol., B: Biology, 5 (1990) 245-254.

  • Röder B.

    Tetrapyrroles: a chemical class of potent photosensitizers for the photodynamic treatment of tumours

    Lecture 2.Plenary Workshop on Tumour Therapy,
    European Community ConcertedAction Programm, Cambrils 1989,
    Abdruck in: Lasers in Medical Science, 5 (1990) 99-106. (invited paper)

  • Röder B.

    Photosensitizing properties of phorbides

    J. Photobiol. Photochem. B: 5 (1990) 519-521. (invited paper)

  • Röder B.

    Tetrapyrroles: a chemical class of potent photosensitizers for the photodynamic treatment of tumours

    Laser Tumour Therapy, ed.: M. Trelles, pp (I-3) - (I-21), 1990

  • Haseloff R., Ebert B., Röder B.

    Generation of free radicals by photoactivation of pheophorbide a, HP and PP

    J. Photochem. Photobiol. B: Biology, 3 (1989) 593-602.

  • Röder B., Wabnitz H.

    Investigation on hematoporphyrin, mesoporphyrin, pheophorbide a and chlorin e6 ethanol and a queous solution by time-resolved fluorescence spectroscopy

    J. Photochem. Photobiol. B: 1 (1987) 103-113.

  • Röder B.

    Pheophorbide a - a new photosensitizer for PDT

    stud. biophys. 144 (1986) 183-186.

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  • Röder B., Hackbarth St., Wöhlecke G.

    US-Patent, NDN 172-0037-2622-7: Dendrimer-photsensitizer complexes for medical applications

    Publication number 00108704 WO vom 08.02.2001

  • Röder B., Hackbarth St., Wöhlecke G.

    Verfahren zur Nutzung von Dendrimeren als Multiplikatoren zur Verabreichung von Photosensibilisatoren

    Patentantrag  vom 02.08.1999, Nr.: 199 36 997.6

  • Röder B., Hackbarth St., Licha S., Riefke J.

    Verfahren zur Nutzung von Tetrapyrrol-Cyclodextrin Wirt-Gast-Komplexen für die in-vivo-Diagnostik

    BRD-Patentantrag  vom 14.09.1995, P 195 35 573.3

  • Röder B., Heinze D.

    Verfahren zum Diagnostizieren von mit fluoreszierenden Substanzen angereicherten, insbesondere tumorösen Geweben

    BRD-Patentantrag  vom 05.11.1991, P 41 26 769.3.

  • Röder B., Nicklisch S., Wischnewsky G., Slawaticki E., Meffert H.

    Mittel zur Behandlung von Hauterkrankungen und Tumoren

    Patent vom 08.10.1984, WP 248 282.